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In a previous trial, retatrutide helped patients lose an average of 28.7% of their weight, outperforming Lilly's blockbuster drug, Zepbound

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By reducing hunger and food cravings, GLP-1 agonists can facilitate more effective weight management during this transitional phase

Some people may experience mild bloating initially, which usually subsides within a few days of regular use

A final consideration regards the financial and ethical sustainability of increasingly expensive drug approaches that some areas of the world have to utilize to combat the deleterious effects of unhealthy lifestyle habits on liver health [21, 45, 46], while other countries still struggle against famine and intermittent access to food [47]