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Head-to-Head Evidence (SURMOUNT-5) SURMOUNT-5 was the first large randomized clinical trial to compare tirzepatide and semaglutide directly at their respective maximum studied doses
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New England Journal of Medicine Jastreboff A.M., Kaplan L.M., Fras J.P., Wu Q., Du Y., Gurbuz S., Coskun T., Haupt A., Milicevic Z., Hartman M.L
7.4 Improvement of translational and clinical research We also emphasize the importance of well-designed animal studies and clinical investigations to validate the safety, efficacy, and mechanisms of gutliver axistargeted interventions, thereby facilitating their potential translation into clinical applications
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