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Central and gastrointestinal axis

In June 2021, the agency approved Wegovy (semaglutide 2.4 mg once weekly) for weight management in adults with a body mass index (BMI) of 30 kg/m or greater (obesity), or a BMI of 27 kg/m or greater (overweight) with at least one weight-related comorbidity such as hypertension, dyslipidemia, or obstructive sleep apnea

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These combined actions result in improved glycemic control, weight reduction, and potential cardiovascular benefits, though specific cardiovascular indications vary by agent according to FDA labeling

This means that visual inspection is a useful but incomplete tool