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13 But there is much evidence that the most obvious consequence is weight gain

What differs is the manufacturing pathway, the regulatory framework, and what goes into the finished preparation

As insulin promotes the translocation of GLUT4 to the membrane through the activation of PI3K-AKT2-PkB pathway, there is a remodeling of the cortical actin of the cytoskeleton with subsequent contraction (Welsh et al., 2010)

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