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1 Patients with type 2 diabetes mellitus (T2DM) pathophysiology includes high glucose toxicity, lipotoxicity and insulin resistance

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This section will explore the mechanisms behind changes in liver enzymes caused by Semaglutide, including how it influences liver enzyme levels, potential cellular and molecular mechanisms, and the role of inflammation and oxidative stress

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These alterations may be further exacerbated by oxidative stress and activation of profibrotic cytokines, such as transforming growth factor , ultimately contributing to the development of chronic kidney disease (82)

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