10.1056/NEJMoa2215024 46
For the first time in the history of obesity medications we see weight loss efficacy of a magnitude that might raise concern about excessive loss of lean body tissue due to the initial pronounced reduction in energy intake and subsequent risk of protein deficiency
Considerations for specific populations Despite the adherence improvement and convenience of GLP-1 patches, they may not be the best option for some people, including: Elderly patients usually have frail skin, making it challenging to apply and remove the transdermal patch
Microdosing GLP-1 medications may be ideal for individuals looking for a gentle on-ramp to metabolic support, those with mild weight concerns, early-stage insulin resistance, or who are prioritizing sustainable lifestyle shifts alongside pharmaceutical guidance, says Dr
Wegovy clinical evidence : The STEP (Semaglutide Treatment Effect in People with obesity) clinical trial programme demonstrated substantially greater weight loss with Wegovy
Business of the American Medical Association House of Delegates 2013 Annual Meeting annotated reference committee reports: reference committee D