In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration) which may cause kidney problems to get worse
While their therapeutic benefits are well-established, the relationship between GLP-1RAs and cancer risk has become a critical focus of clinical investigation
Terrelonge M, Marder KS, Weintraub D, Alcalay RN
The most widely used ones right now are semaglutide (sold as Ozempic for diabetes management and Wegovy for weight loss) and tirzepatide, which targets both GLP-1 and a second hormone called GIP (Mounjaro for diabetes, Zepbound for weight loss)
When levels fall behind, the effects show up in the places athletes care about most: recovery time, sustained energy, muscle repair, and immune resilience
Use is most often described after age-related collagen decline becomes visible, commonly from the mid-30s onward