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Brain 138(Pt 6):17381755
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The article says evidence suggests estrogen modulates GLP-1 receptor expression in hypothalamic appetite centres, so as estrogen falls, GLP-1 signalling efficiency may diminish and compound existing metabolic challenges
For instance, selenoproteins S (SELENOS), N (SELENON), M (SELENOM), T (SELENOT), and F (SELENOF, previously known as 15 kDa selenoprotein (Gladyshev et al., 2016) are endoplasmic reticulum-associated proteins, involved in the unfolded protein response (Ye et al., 2005) and, potentially, other less explored functions
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