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7 Still, Le, who is also a general surgery registrar at Royal Melbourne Hospital, says, I think it is too early to say this is a robust, durable, and generalizable effect given the high heterogeneity of underlying studies. He notes a need for more rigorous randomized controlled trials with longer follow-up times to better characterize the impact of these medications on weight and OSA together, as well as gain a better understanding of effect size, optimal doses, side effects, interactions with other medications, and impacts on other comorbidities

RETA led to remarkable improvements in body composition with a significant reduction in epididymal adipose mass quantified at endpoint as compared to Veh (Fig

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was supported by National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases grants (P30 DK040561, U24 DK132733, and UE5 DK137285)