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Libraries for RNA-seq were prepared at the IRB Barcelona Functional Genomics Core Facility

The compound then received GRAS (Generally Recognized as Safe) designation from the FDA for use as a food ingredient, which is a separate regulatory category from drug approval

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Overall, the study demonstrated that AOD9604 affects metabolic parameters in both lean and obese mice, as well as in genetically modified mouse models lacking 3-adrenergic receptors