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We found that treatment with DTT led to almost complete reduction of albumin in otherwise untreated cells, whereas etomoxir caused a significant increase in the preponderance of albumin that remained oxidized (Figure 4A)

We're in a high throughput proteomics era right now that we can analyze thousands of plasma proteins in any given individual

Bias between mini-G s and -arrestin-2 recruitment was determined similarly to earlier work (Pickford et al ., 2020), by subtracting the log /K values (Kenakin et al ., 2012) for each ligand in each pathway for each assay to determine log /K A (referred to here as LogR)

Research has used MT-1 in EPP models to characterise the mechanisms through which MC1R activation protects against protoporphyrin-mediated phototoxicity