Michael Donnino introduced the term gastrointestinal beriberi (63) to describe a distinct clinical entity caused by TD in the gastrointestinal system
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however, many of these studies have small sample sizes, typically involving fewer than 50 participants (Nie et al., 2023)
It has been granted GRAS (Generally Recognized as Safe) status by the FDA for use as a food supplement ingredient, though this is distinct from drug approval
Previous studies demonstrated that PCYT1A , GPAT4 and DGAT2 are responsible for increasing the size of LDs 18,19,20