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Anaemia, megaloblastic Treatment summaries (BNF/NICE)
All examined the effect of combined folate and vitamin B12 supplementation (most with vitamin B6 or pyridoxine as well) on the rate of thrombotic vascular events in high-risk subjects
89 , 693S696S (2009)
This may present as a subacute progressive decrease in visual acuity with a cecocentral scotoma (ie, a scotoma obscuring central vision and enlarging the blind spot)
Routine serum B12 measurement is not useful once on injection therapy
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