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Common risk factors for NAION include: Diabetes High blood pressure High cholesterol Sleep apnea Small or crowded optic nerves Smoking Cardiovascular disease Older age These risk factors are important because many patients who take GLP-1 medications may already have diabetes, obesity, sleep apnea, or vascular risk factors that can also increase NAION risk

Due to this risk, a doctor will likely not prescribe Mounjaro if you or a family member has had medullary thyroid cancer or multiple endocrine neoplasia syndrome 2 (MEN 2)

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7ad), even though it promoted the accumulation of GSH in cells (Extended Data Fig