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Without proactive dose reductions and frequent glucose checks, users can experience symptomatic lowssweating, tremor, confusion, palpitationsor severe events requiring assistance
STEP 4 is the important counterpoint: weight came back when treatment stopped, so this is a long-term treatment rather than a short course, and whether it is right for you is a decision for the prescribing doctor
& Neff, L
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Clinical trials show an average loss of 515 pounds in the first 12 weeks, though this varies widely based on starting weight, genetics, and lifestyle adherence
Eligible adults typically have: A BMI 35 kg/m and at least one weight-related comorbidity, or A BMI between 3034.9 kg/m when meeting specialist referral criteria (lower thresholds may apply for some ethnic groups) When restarting after an extended break, healthcare providers should: Reassess the patient's current weight and comorbidities Review the reasons for treatment interruption Ensure contraindications have not developed during the break Discuss realistic expectations for weight loss trajectory Reinforce dietary and lifestyle modification strategies Patients should be counselled that restarting at the lowest dose is a safety measure, not a setback
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