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NO bioavailability is thereby maintained, endothelium-mediated vasorelaxation is preserved, and vascular remodeling and fibrosis are prevented

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We wanted to look at this systematically in part to address the Catch-22 of third-party payers declining to cover these anti-obesity drugs because people quit them at a higher rate, when in truth some people stop the medications because coverage was terminated by the insurance company or the patient failed pre-authorization or they simply can't afford the out- of-pocket cost. Data is also important for clinicians and patients, he adds