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Furthermore, VEGF may also increase the permeability of blood vessels, which might enable the extravasation of plasma proteins and contribute to the formation of a primitive vascular scaffold, thereby potentially promoting the process of angiogenesis
To counter this limitation, a group of GLP-1 receptor agonists (GLP-1RAs), which are resistant to DPP4-mediated degradation [32], have been developed and shown to be effective in treating T2DM and obesity [33]
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GLP-1 is a hormone that lowers hunger and food-seeking behaviours by communicating with the brains appetite control centre, the hypothalamus
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