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Most patients achieve significant weight loss at doses between 1.0 mg and 2.0 mg weekly
Quignot, C
Some studies have explored sexual function in patients using GLP-1 receptor agonists more broadly
A meta-analysis of 12 randomized controlled trials found berberine produced approximately 4.5 pounds of weight loss on average, significantly less than prescription GLP-1s but more than placebo
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Joy also emphasized the importance of proper hydration when taking creatine, as it will draw water into muscle cells and increase your need for water. Creatine is generally safe for healthy individuals at standard doses, though mild gastrointestinal symptoms or water retention can occur
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