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Some studies pair them, and there's a plausible reason: vitamin C helps regenerate active glutathione in the body, and both are studied for antioxidant and pigmentation-related effects

doi: 10.1016/j.neulet.2008.06.028 93 JiangH.LingZ.ZhangY.MaoH.MaZ.YinY.et al

By characterizing GSHs function and designating it as a special regulator of immune cell behavior, this review highlights its potential as both a therapeutic agent and biomarker for patients with neurodegenerative conditions

Symptoms of a Herxheimer reaction include a sudden, intense exacerbation of baseline symptoms: severe brain fog, debilitating fatigue, migrating joint pain, flu-like body aches, headaches, and heightened anxiety