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Yadav S, Laue TM, Kalonia DS, Singh SN, Shire SJ
The treatment group showed significant reductions in body weight (approximately 5% loss) and white adipose tissue mass (35% reduction) compared to control animals, despite no changes in food intake
Toxicology and applied pharmacology 257 , 338348, doi: 10.1016/j.taap.2011.09.017 (2011)
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On the contrary, activation of the TSS pathway under physiological cystine supplement is achieved under DMF treatment through enhanced CBS expression and cystine uptake to protect against ferroptosis in SCD erythroblasts