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More specifically, vitamin B12 plays an important role in DNA synthesis, which itself is vital for cellular reproduction

Autoantibodies targeting the same epitope of CD320 were identified in seven other patients with neurologic deficits of unknown etiology, 6% of healthy controls, and 21% of a cohort of patients with neuropsychiatric lupus (200)

Further, none of the studies cited above included large numbers of patients with neurologic deficits, although significant improvement occurred in the limited number of orally treated patients with such deficits

They are not approved for human or veterinary use

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