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p53-pS15 is a major focal point in p53 activation to mediate p53-dependent transcription or growth arrest, Ser 15 phosphorylation triggers a sequence of additional sites phosphorylation in p53 (including Ser9, -20, -46 and Thr18) that contribute further to p53 activation 28
D.et al (1985)
Similarly, lymphoblastoid B-cell lines (LCLs), non-tumor cell lines created through the immortalization of normal B-cells from healthy donors using the Epstein-Barr virus (EBV), do not grow in 3D gels [28, 29]
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