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The medication creates measurable, sometimes dramatic changes across multiple blood markers

A recently published survey conducted among Israeli endocrinologists, internal medicine physicians and family physicians who practice obesity medicine reported that fewer than 50% of physicians discussed treatment duration with their patients, and 52% of patients discontinued therapy in the first 3 months

Notably, Il1b was identified as a highly connected candidate gene, both in terms of its network degree and its well-documented role in metabolic and inflammatory regulation, suggesting it may play an important role in relevant signaling pathways

This practice, known as stacking, creates a synergistic effect

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