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If you wish to discontinue therapy with our hormonally active substances, you should not do so abruptly, but should reduce the dosage gradually over a period of 4 to 5 weeks in consultation with your doctor

A 2.6% reduction in a single year of semaglutide therapy on top of that baseline rate is clinically meaningful, particularly for patients who are already in an at-risk category

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To do so, we employed a repeated measures within-subject design in which a single blood draw from each animal was processed in four different ways (see Fig