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Clinically, this can manifest as vasodilatory shock, pulmonary dysfunction, coagulopathy, arrhythmias (like atrial fibrillation), and AKI (168)

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The link between GSTP and cancer is most obvious in the overexpression of GSTP in many cancers, but it is also supported by the fact that the transformed phenotype of tumor cells is associated with aberrantly regulated kinase signaling pathways and cellular addiction to overexpressed proteins

This medication works by inhibiting pancreatic lipase, reducing dietary fat absorption by approximately 30%