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Immune-cell activation can reorganize nutrient use, NADPH production, mitochondrial metabolism, and thiol-dependent signaling, making glutathione regulation one component of broader immunometabolic control

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Figure 6 Discussion Non-genetic mechanisms have recently emerged as important drivers of cancer therapy failure, whereby some cancer cells enter a reversible drug-tolerant persister state in response to treatment ( et al

We found that the inhibition of proteasome machinery amplify the virus-induced impairment of NHEJ pathway (by 70% vs