These cells appeared to produce trophic factors, preserve neuromuscular function, and reduce astrogliosis and inflammation [153]
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Its anti-inflammatory mechanisms are enacted through the downregulation of pro-inflammatory cytokines such as IL-1, IL-6, and TNF-, along with the inhibition of NF-B signaling, thus alleviating neuroinflammation that is implicated in the etiology of depressive disorders (54)
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