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Phase 3 TRIUMPH-4 showed 28.7% weight loss at 68 weeks, substantially exceeding CagriSema's 20.4% at 68 weeks
Accepted: Apr 16, 2025 DOI: Download citation
In diet-induced obese and genetically obese/diabetic mouse models, this molecule showed stronger effects than GLP-1GIP co-agonism, semaglutide, or lanifibranor alone in reducing body weight, food intake, and hyperglycaemia
The group receiving the combined treatment experienced a 15.6% reduction in weight loss, while the groups receiving treatment with cagrilintide or semaglutide experienced an 8.1% and 5.1% reduction in body weight, respectively [2]
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