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Both drugs have been approved for use in Canada, Ozempic since 2018 and Wegovy since 2021
Medication adjustments may be considered in consultation with prescribing clinicians: Dose reduction : Lowering the Ozempic dose may reduce symptom severity whilst maintaining some glycaemic benefit Slower titration : Increasing the dose more gradually than standard protocols may improve tolerability Prokinetic agents : In the UK, medications such as metoclopramide are generally restricted to short-term use (maximum 5 days) due to neurological side effect risks
Curcumin remarkably reduces malondialdehyde (MDA) and nitrotyrosine levels and induces superoxide dismutase (SOD) and glutathione peroxidase (GPx) post-TBI (Hakiminia et al., 2022)
GLP-1 side effects and treatment can vary from person to person
Supplements Certain supplements can support glutathione levels
Do not assume that a medication should be restarted at the same dose after a treatment gap
