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61 SecherA.JelsingJ.BaqueroA

For more information, please refer to the individual studies cited in the manuscript

This important preclinical study showed that ketamine and other NMDAR antagonists produce fast-acting antidepressant-like effects in mouse models that depend on the rapid synthesis of BDNF via a mechanism that includes the deactivation of eEF2 kinase

One potential advantage of berberine is that since it has a different mechanism of action from metformin and statins, it may be useful for patients who dont respond well to these first-line treatments

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Aim to consume roughly 70% of your daily fluids before dinner