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One big disadvantage is that they don't provide much fiber

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202 An analysis of 30 randomized controlled trials encompassing over 1,600 subjects found those treated with probiotics had on average 7.8 point-lower total cholesterol and 7.3 point-lower LDL levels than those not treated

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Its going to be worst around day 2 and then start to taper off

Although the findings were promising, the studys credibility is tempered by its small sample size (n = 10), short duration of treatment, and the absence of detailed dietary intake data during the trial period [112]