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Am J Med Genet C 142C:7785 Szabo K, Nagy Z, Juhasz V, Zolnerciks JK, Csorba A, Timar Z, Molnar E, Padar P, Johnson W, Beery E, Krajcsi P (2016) Species specificity profiling of rat and human organic cation/carnitine transporter Slc22a5/SLC22A5 (Octn2/OCTN2)

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While the models share hormonal changes and satiety impairments, Bbs5 / mice displayed a unique immune profile characterized by elevated macrophages, a skewed M1/M2 balance, and Tregs with Th17-like phenotypes, resulting in a proinflammatory signature

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