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PloS One (2013) 8:e54518

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Recent postmarketing data (reports from people whove used the medication since it became available for use) has also identified more serious complications , including ileus (a type of intestinal blockage) and severe constipation leading to fecal impaction

We need to make sure that patients prescribed these medications arent already at risk for malnutrition or low muscle mass. About GLP-1 Drugs While GLP-1 drugs help people lose fat, this comes with loss of fat-free mass, of which muscle makes up 40% to 50%

Treatment of constipation in older adults

Oxidative stress in amyotrophic lateral sclerosis: pathophysiology and opportunities for pharmacological intervention