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The primary concern at high doses (3g+) is the potential for elevated TMAO levels via gut bacteria conversion, though the clinical significance of this at moderate supplemental doses is debated

These hormonal issues increase weight in perimenopausal women and further increase our risk for heart disease and stroke, she adds

Indeed, increased insulin secretion has been noticed in thyrotoxicosis in some early studies, which was usually considered as a compensatory response to lower the elevated blood glucose levels 37,38

Potentially, pharmacological enhancement of incretin secretion could bridge the gap between RYGB and LAGB on body weight and diabetes-related outcomes

Furthermore, the homeostasis of bone formation and resorption is essential to bone health and might be maintained by GLP-1 in normal bones and restored by GLP-1 in unhealthy bones

Compounded formulations are also HSA- and FSA-eligible, providing additional tax-advantaged savings