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In DKD, cellular stress caused by abnormal stimulations, such as hyperglycemia, hyperlipidemia, and hypoxia, leads to mitochondrial dysfunction which eventually induces apoptosis

Parasympathetic efferent nerves can transmit neuropeptides and acetylcholine to the islet liver, increasing insulin release and liver NO production through muscarinic receptors and lowering blood sugar

The anti-inflammatory effects of KPV complement the regenerative effects of BPC-157

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J Dental Sci