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APAP feeding resulted in a significant decrease in total glutathione levels relative to vehicle control, with greater than a 70% reduction in total GSH levels after 3 days of exposure (116.42 5.55 uM GSH for vehicle control vs 33.67 2.35 for APAP treated)

Comparative analyses of GLP-1RAs with other glucose-lowering agents reveal distinct safety profiles, emphasizing the critical importance of patient-specific treatment strategies