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J Funct Foods 109:105787

When antibiotics, particularly sulphur drugs, are used for extended periods, the normal synthesis of Folic acid in the gut will be reduced and the requirements for Folic Acid are increased.

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Moreover, nanoparticles must navigate through the brain's extracellular space after traversing the BBB, which constitutes approximately 20% of the brain's total volume and is generally around 20 nm wide

J Biol Chem 280 , 3376633774, doi: 10.1074/jbc.M504604200 (2005)

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