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Apoptosis-inducing factor (AIF) and its family member protein, AMID, are rotenone-sensitive NADH:ubiquinone oxidoreductases (NDH-2)
Jayakumar et al
It is also known for its calming feel in many formulas
Summary While NAC is considered safe as a prescription medication, it can cause nausea, vomiting, and gastrointestinal disturbances, as well as mouth issues if inhaled
Reduction of ScGrx7 by GSH is slower than the oxidation by GSSCys (unless Lys105 is replaced, which decelerates the oxidative half-reaction even more than the reductive half-reaction owing to the dual activator function)
