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GSSG increased the level of intracellular ROS, but to a lesser extent than hydrogen peroxide

JAMA 306 , 15491556 (2011)

headaches, brain fog, GI irregularity, dizziness, and other complications

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Iron overload increases ferritin levels and decreases RUNX2 levels in BMSCs, causing irregular morphological changes, significantly reducing their activity, and inhibiting osteogenic differentiation, while melatonin therapy could reverse this process and promote osteogenic differentiation of BMSCs

Tissue Engineering Regenerative Medicine 15 (3), 341350