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Prebiotics, such as inulin, fructooligosaccharides, and galactooligosaccharides, are dietary fibers that resist digestion in the upper gastrointestinal tract and selectively stimulate the growth or activity of beneficial bacteria in the colon (121, 122)
Another GLP-1 analogue, lixisenatide, was reported to prevent the acuteness of cardiovascular events in apolipoprotein E / insulin receptor substrate 2 +/ (APOE / irs2 +/ ) mice by reducing the size of AS plaques, increasing plaque stability, and promoting the conversion of macrophages to the anti-inflammatory M2 phenotype (129)
However, the two drugs had not been directly compared in this context
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Nabiel Y, ELshahawy H, Mosbah A
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