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Researchers measured how long it took for half a meal to leave the stomach in people on a GLP-1 drug versus a placebo
The highest probabilities of equivalence were observed for semaglutide 2.4 mg vs tirzepatide 10 mg (99.4%) and semaglutide 7.2 mg vs tirzepatide 15 mg (94.8%)
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In adjusted analyses, semaglutide reduced epigenetic aging across multiple second- and third-generation clocks, including PhenoAge ( 4.9 years/year, p = 0.004), PCGrimAge ( 3.1, p = 0.007), GrimAge V2 ( 2.3, p = 0.009), OMICmAge ( 2.2, p = 0.009), RetroAge ( 2.2, p = 0.030), and DunedinPACE ( 0.09 units, 9% slower, p = 0.01)
Ideal for enhancing physical endurance and overall vitality
No oral semaglutide
