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Understanding these peptide mechanisms at molecular detail helps optimize clinical applications

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In animal studies, Epithalon has been shown to: Increase average and maximum lifespan Reduce chromosomal aberrations Delay the onset of age-related diseases Improve neuroendocrine function and melatonin secretion Regulate gene expression related to longevity Perhaps most notably, Epithalon has been found to reactivate telomerase , an enzyme that rebuilds telomeres and potentially resets the cellular aging clock

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Additionally, data from a Phase I clinical trial (NCT02861300) indicated that the combination of CB-839 and capecitabine which is a prodrug of 5-FU, was well tolerated by CRC patients at bioactive doses