Nearly a decade later, the Food and Drug Administration (FDA) issued the first approval for a GLP-1 analog to treat obesity
British Journal of Nutrition, 135 (9), 956963
Subsequent reports based on pharmacovigilance data, post hoc analyses of randomised trials, and findings from observational studies indicate a potential link between GLP1 receptor agonists and thyroid cancer
Two recent studies that included individuals with and without type 2 diabetes found that GLP-1 contributed ~50% of the glucose-lowering and insulin-stimulatory effects of DPP-4 inhibitors [2, 18]
Klopstock TF, Tricta L, Neumayr, et al
NNMT is examined as a target in metabolic disease and cancer research, and 5-Amino-1MQ is frequently used as a pharmacological tool compound in that research context