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International Journal of Molecular Sciences 19

Molecules , 19 (11), 1906619077

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This can lead to symptoms such as: Stomach pain or discomfort Heartburn or indigestion Nausea In severe cases, ulcers or gastrointestinal bleeding People who take ibuprofen frequently or in high doses, have a history of stomach ulcers, or are older adults are at higher risk of experiencing stomach pain or more serious complications

It's an open question as to whether other GLP-1 drugs like tirzepatide the active ingredient in Mounjaro and Zepbound have similar issues, VanderBeek says