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Diabetes Care 41 , 258266 (2018)

7) is characterized by concurrent obesity and IR, with AT inflammation and apoptotic dysregulation as core features [189, 190]

According to research, data from trials like STEP 1 and SUSTAIN 8 indicates that approximately 40% of the weight lost by patients taking semaglutide can be attributed to lean mass, primarily muscle tissue, raising concerns about potential cardiovascular and bone health risks due to muscle loss

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