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Holden JL et al
In subjects with baseline glucose disposal rates below 7.9 mg/kg per minute, acetyl-L-carnitine treatment significantly increased insulin sensitivity and improved glucose tolerance, with some individuals transitioning from impaired glucose tolerance to normal glucose metabolism
doi:10.1038/s41598-021-00353-z
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In the trial, patients with type 2 diabetes, which was poorly controlled with metformin, received Ginkgo biloba extract supplementation
GLP-1R is widely expressed in the whole body, mainly in the lungs, kidneys, heart, adipose tissue, and the central and peripheral nervous systems [3]
