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Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: an interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials

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Lancet 402:529544

doi: 10.1016/j.bbi.2009.05.058 62 GaultV

The approved dosing regimen begins at 0.25 mg once weekly for four weeks (an initiation dose to improve tolerability), then increases to 0.5 mg once weekly, with further increases to 1 mg or 2 mg if needed for glycaemic control