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This combines restriction with malabsorption for powerful metabolic effects
L., Horberg, M., Koebnick, C., Oshiro, C., Yamamoto, A., Young, D
doi: 10.1176/appi.ajp.162.8.1423 109 O'ConnorR
I suspect this is from the glucagon agonism of the drug as glucagon stimulates the formation of extra bile acids/bile salts in the liver which can be very irritating to the intestinal lining causing diarrhea
It was developed by Novo Nordisk and described by Raun et al
Specifically, with 4.5 mg dulaglutide, the weight reduction was 5.0 kg at 52 weeks of treatment [120]
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