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They should be willing to commit to a long-term treatment plan that includes regular monitoring by healthcare professionals, adjustments to their lifestyle, and adherence to a reduced-calorie diet paired with increased physical activity
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Nature communications 2025
All patients will be prescribed medication to alleviate nausea
Research has shown that calorie-restricted diet interventions in random human subjects, while improving metabolic health, lead to a reduction in bacterial numbers and a reshuffling of the gut microbiota due to strict calorie restrictions (von Schwartzenberg et al., 2021)
The drug performed better on all secondary endpoints as well, including a greater percentage of people losing at least 15% of their weight (roughly a third of those on the highest dose achieved this)
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