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Compared with controls, the researchers observed: Fewer beneficial gut bacteria involved in breaking down dietary fiber Lower levels of short-chain fatty acids, compounds that help support the gut lining and play a role in inflammation control Higher levels of inflammatory markers in the blood Increased liver weight, which can be consistent with low-grade inflammation A smaller cecum the part of the intestine where gut bacteria break down fiber and produce protective compounds Reduced levels of a brain-derived protein associated with cognitive impairment Taken together, the results suggest SNAC may influence the gut ecosystem and inflammation-related pathways, not just medication absorption
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doi: 10.1016/j.ctim.2019.102273 59
The medication works through multiple mechanisms that may influence appetite regulation and food preferences, including those for sweet foods
If youre in a sexual relationship that can result in pregnancy, use at least one form of birth control unless youre planning on getting pregnant